This research has been carried out in order to analyze and explain the structure-agent interaction in the evolution process of I.R. Iran's nuclear case. The theoretical framework of this research for qualitative data analysis is constructivist theory and the categories of "identification" and "structure-agent" and a quantitative questionnaire was also used to justify the findings. In this regard, in order to answer the questions and analyze the hypotheses of the research, the nuclear case of Iran from the time of its formation until the Joint Comprehensive Plan of Action (JCPOA), in the 8th, 9th, 10th and 11th governments based on the relations of the structure (system) International)-broker (governments of Iran) has been examined and analyzed. The findings of the research show that in the reform government, despite the interactive approach of the agent (Iranian government), the structure (international system) did not agree to recognize Iran's nuclear identity.
During the presidency of Mahmoud Ahmadinejad, due to the "look and mentality" as well as the experience of the previous period of Iranian officials and mistrust of the West and adopting a confrontational approach of the agent (Iranian government) as well as the lack of interaction from the international system, interaction between Iran and The international system was not formed regarding the nuclear case. During the period of Hassan Rouhani, due to the adoption of the interactive approach of the Iranian government and the change of view and as a result of adjusting the demands of the international system, the interaction between the structure and the agent was formed and Iran's nuclear program was accepted and recognized by the international system. Therefore, from the perspective of this research, one of the influencing factors on Iran's nuclear case has been the type and degree of interaction between the two sides of the nuclear case.